I-China Hot Sale CAS 2160555-52-0 5CAKB48 amandla amhlophe ama-cannabinoids
Isakhiwo samakhemikhali
Omqondofana
5CAKB48;
5CI-ADB-A;
5CI-ADB-A powder;
1H-Indazole-3-carboxamide, 1-(5-chloropenyl)-N-tricyclo[3.3.1.13,7]dec-1-yl-
I-Chemistry
I-5F-AKB48, noma i-N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, iyi-indazolecarboxamide yokwenziwa njengoba iqukethe iqembu le-indazole elifakwe esikhundleni.Le moeity ye-indazole ishintshwa ngo-R1 ngeketango le-fluoropentyl, esikhundleni salo okwabelwana ngaso ne-5F-PB-22.Ukwengeza, i-indazole ithathelwa indawo ngo-R3 neqembu le-carboxamide.Leli qembu le-carboxamide lifakwe esikhundleni se-N eqenjini lalo le-amine elineqembu le-adamantane.Leli qembu liqukethe izindandatho ezine ezihlanganisiwe ze-cyclohexane esakhiweni esiyingqayizivele esibizwa ngokuthi i-diamoid.I-5F-AKB48 iyi-analogue ye-STS-135 lapho uhlaka lwe-indole eyinhloko lushintshwa ngesisekelo se-indazole.
Imiphumela engokomzimba
Ukuzwa komzimba okuzenzakalelayo
"Ukuphakama komzimba" kwe-5F-AKB48 kungachazwa njengokuzwakala okubukhali, okungakhululekile, okuhlanganisa konke, kanye nokugedla kukagesi okusabalala emzimbeni ngemva kokumunywa kokuqala.Igcina ubukhona obufanayo obukhuphuka ngokushesha lapho kuqala futhi ifinyelele umkhawulo wayo uma isiqongo sesifinyelelwe ngaphambi kokuhlakazeka ngokushesha.
Ukulahleka kokulawulwa kwezimoto -
Le nto idala ukucindezelwa okuyingxenye noma okulingene kokulawula ukunyakaza okuqinisa ukulingana nomthamo, kodwa akuvamile ukuthi kuphumele ekungakwazini ngokuphelele ukuhamba nokwenza ukunyakaza okuyisisekelo.
Ukuthuthukisa isifiso sokudla
Njengamanye ama-cannabinoids amaningi, i-5F-AKB48 ibangela ukwanda kwesifiso sokudla, eyaziwa ngokuhlanganyela ngokuthi "ama-munchies" esikweni elidumile laseMelika nase-United Kingdom.Izifundo zemitholampilo kanye nedatha yenhlolovo ithole ukuthi i-cannabis inyusa ukujabulela ukudla kanye nentshisekelo ekudleni.Lokhu kucatshangwa ukuthi kungenxa yendlela ama-endocannabinoids ku-hypothalamus asebenza ngayo ama-cannabinoid receptors anesibopho sokugcina ukudla.
Ukunciphisa ubuhlungu
Ama-cannabinoids akhonjiswe emtholampilo ukuthi ahlinzeka ngokukhululeka kobuhlungu nge-agonism yama-cannabinoid receptors CB1kanye CB2, okudlulela kuma-agonists okwenziwa kwama-cannabinoid receptor.
Ukubona ukukhanya komzimba
Izinguquko kumandla adonsela phansi
Ukuphelelwa amanzi emzimbeni
Lokhu kwaziwa ngokwezwi nezwi ngokuthi "umlomo kakotini" esikweni elidumile laseMelika nase-United Kingdom.
I-Vasodilation
2.Isiphi isikhathi esijwayelekile sokuhola?
3.Ithini imigomo yakho yokuthumela?
Izindlela ezisheshayo: i-FDEX, i-DHL, i-UPS, i-TNT, njll ngolwandle noma ngokonga komoya
4.Isebenza kanjani imboni yakho mayelana nokulawulwa kwekhwalithi?