I-China Hot Sale CAS 7361-61-7 Xylazine cannabinoids powder emhlophe
Isakhiwo samakhemikhali
Amazwi afanayo:
2-(2,6-dimethylanilino) -5,6-dihydro-4h-1,3-thiazine;
2-(2,6-dimethylphenylamino) -4h-5,6-dihydro-1,3-thiazine;
5,6-dihydro-2- (2,6-xylidino) -4h-1,3-thiazine;
5,6-dihydro-2- (2,6-xylidino) -4h-3-thiazine;
I-2-(2,6-Dimethylphenylamino) -5,6-dihydro-4H-thiazine;
I-Xylazine Base & HCL;
I-Xylazine, i-2-(2,6-Dimethylphenylamino) -5,6-dihydro-4H-thiazine hydrochloride;
I-Xylazine (200 mg)
Incazelo
I-Xylazine i-agonist ye-α2-adrenergic receptors (Ki = 194 nM).Kuyi-analog ye-clonidine, i-α2-adrenergic receptor agonist esetshenziselwa ukwehlisa umfutho wegazi.I-Xylazine isetshenziselwa i-sedation, i-anesthesia, ne-analgesia ezilwaneni ezincelisayo ezingezona abantu.Lo mkhiqizo uyatholakala futhi njengezinga lereferensi yokuhlaziya .
Umsunguli i-Xylazine, i-Bayer
Isebenzisa
I-Antinociceptive;i-Alpha-2 adrenergic agonist
Isebenzisa
I-Xylazine iyisigaba se-α2 se-adrenergic receptor agonist.I-Xylazine iyi-analoque ye-clonidine esebenza kuma-presynaptic kanye ne-postsynaptic receptors njenge-agonist ye-2-adrenergic.
Inqubo Yokukhiqiza
I-2,6-Dimethylphenyl isothiocyanate, i-31.0 g (i-0.2 imvukuzane), elungiselelwe kusuka ku-2,6- dimethylaniline ene-thiophosgene, yengezwe nge-dropwise phakathi ne-15 min ukuya ekumisweni okugqugquzelwe kahle kwe-15.0 g (0.2 imvukuzane) ye-3-aminopropanol-1 ku- 100 ml ye-ether.I-ether yaqala ukubila.Ukugqugquzela ngaphansi kwe-reflux kwaqhubeka imizuzu engu-30, futhi i-ether yabe isikhishwa.Izinsalela zaphathwa nge-100 ml ye-concentrated hydrochloric acid futhi ibilisiwe ngaphansi kwe-reflux imizuzu engu-30.Ngemva kokupholisa, yayihlanjululwe ngamanzi, ihlungwe ngaphandle kokungcola, futhi isisekelo sancishiswa ngokufakwa kwesisombululo se-sodium hydroxide.Lapho ihlanganiswa kabusha isuka ku-benzene-ligroin, inhlanganisela engu-2-(2,6- dimethyl-phenylamino)-4H-5,6-dihydro-1,3-thiazine, indawo yokuncibilika 140-142°C (ikhiqiza u-90% wethiyori. ).
Umsebenzi Wokwelapha
I-analgesic, i-anesthetic
Incazelo evamile
I-Xylazine iyancibilika ku-methanol (50 mg/ml), ikhiqiza isisombululo esicacile, esingenambala.Iphinde inyibilike ekuxubeni i-HCl acid naku-chloroform.I-Xylazine ayincibiliki emanzini nasezixazululweni ze-alkali.
Izenzo ze-Biochem/physiol
I-Xylazine uma isetshenziswe kanye ne-ketamine ibhekwa njenge-anesthetic enamandla futhi ephephile esilwaneni sokuhlola.Kuyaziwa ukuthi inyusa ukukhululwa kwe-glucose esibindini, okubhebhethekisa i-hyperglycemia.
Indlela yokwenza
I-Xylazine imakethwa njengosawoti wayo we-hydrochloride njenge-Rompun (100 mg/mL) kanye ne-Anased (20 mg/mL) izixazululo ezijovayo zokuphathwa komjovo kumahhashi nezinja, ngokulandelana.Izenzo ze-xylazine zingahle ziguqulwe ngokuphathwa kwe-yohimbine, i-indoalkylamine alkaloid, evimba lawo ma-α2-adrenoreceptors akhuthazwa yi-xylazine.
Iphrofayela Yokuphepha
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