I-Epithalon CAS:307297-39-8 EpithalonAcetate Glycine 55 ibangwa amaprotheni

Ucwaningo lwe-in vivo lwamagundane asebekhulile lwathola ukuthi ukwelashwa kwe-epitalon kwehlise kakhulu izehlakalo zokuphambuka kwe-chromosomal kuwo womabili amagundane ohlobo lwasendle namagundane abonakala nge-phenotype yokuguga esheshayo, eyayihambisana nokwanda kobude be-telomere.

Olunye ucwaningo lwamagundane asebekhulile lwathola ukuthi i-epitalon yandisa umsebenzi we-antioxidant enzymes superoxide dismutase, glutathione peroxidase, ne-glutathione -S-transferase.

Ekuhlolweni kwamagundane esifazane anonyaka owodwa i-C3H/He, i-Epitalon yehlisa inani lamathumba azenzekelayo kanye nenani lama-metastase kumagundane avele avele avele azenzekele, futhi kwacatshangwa ukuthi inokucindezela isimila kanye nezindawo zokulwa ne-metastatic.

Ocwaningweni lwezinkukhu ezitholwa yi-neonatal pituitectomy kanye nokuvuthwa okwalandela, i-epitalon yakhuthaza ukubuyiswa kwesakhiwo se-morphological ye-thymus, kanye nokwakheka nokusebenza kwendlala yegilo.

I-Epitalon ibonakala ikhulisa ukwanda kwe-lymphocyte ku-thymus, okungenzeka ukuthi ikhulisa i-interferon gamma ekhiqizwa ama-T cell.

Olunye ucwaningo kumagundane amadala lubonise ukuthi ukukhanya okungaguquki, noma uhlobo lokukhanya lwemvelo oluvamile ezifundeni ezisenyakatho, kwandisa isikhathi sokuphila samagundane.